This Italian Bison Meatloaf is a delightful twist on the classic comfort food, combining the rich, lean flavor of bison with traditional Italian herbs and cheese. Perfect for a hearty dinner, this dish is both nutritious and delicious, making it a great choice for those looking to try something new while still enjoying familiar flavors.
Ground bison might not be a common ingredient in every household, but it can usually be found in the meat section of most supermarkets or specialty stores. It's leaner than beef and offers a unique flavor. Marinara sauce is another key ingredient; while it's widely available, make sure to choose a high-quality one for the best results. Parmesan cheese should be freshly grated for optimal taste.

Ingredients for Italian Bison Meatloaf
Ground bison: Lean and flavorful meat, a healthier alternative to ground beef.
Breadcrumbs: Helps bind the meatloaf together and adds texture.
Egg: Acts as a binder to hold the meatloaf together.
Parmesan cheese: Adds a rich, savory flavor to the meatloaf.
Dried oregano: Provides a classic Italian herb flavor.
Dried basil: Complements the oregano with a sweet, aromatic touch.
Salt: Enhances the overall flavor of the dish.
Black pepper: Adds a bit of heat and depth to the flavor.
Marinara sauce: Used both in the meat mixture and as a topping, it adds moisture and a rich tomato flavor.
Technique Tip for This Recipe
When mixing the ground bison with the other ingredients, be careful not to overwork the meat. Overmixing can lead to a dense and tough meatloaf. Instead, gently fold the breadcrumbs, beaten egg, grated parmesan cheese, and spices into the bison until just combined. This will help maintain a tender and juicy texture.
Suggested Side Dishes
Alternative Ingredients
ground bison - Substitute with ground beef: Ground beef has a similar texture and flavor profile, making it a suitable alternative.
breadcrumbs - Substitute with crushed crackers: Crushed crackers can provide a similar binding effect and texture.
beaten egg - Substitute with flaxseed meal and water: Mixing flaxseed meal with water creates a gel-like consistency that can act as a binder.
grated parmesan cheese - Substitute with grated pecorino romano: Pecorino romano has a similar salty and tangy flavor, making it a good replacement.
dried oregano - Substitute with dried thyme: Dried thyme offers a similar earthy and slightly minty flavor.
dried basil - Substitute with dried marjoram: Dried marjoram has a sweet and mild flavor that can mimic dried basil.
salt - Substitute with soy sauce: Soy sauce can add a similar level of saltiness along with a bit of umami flavor.
black pepper - Substitute with white pepper: White pepper provides a similar heat and flavor without altering the color of the dish.
marinara sauce - Substitute with tomato paste and water: Mixing tomato paste with water can create a similar consistency and flavor to marinara sauce.
Other Alternative Recipes Similar to This Dish
How to Store or Freeze This Dish
- Allow the Italian bison meatloaf to cool completely before storing. This helps prevent condensation, which can make the meatloaf soggy.
- Wrap the meatloaf tightly in plastic wrap or aluminum foil. This helps to keep it fresh and prevents it from absorbing any unwanted odors from the fridge.
- Place the wrapped meatloaf in an airtight container. This adds an extra layer of protection and ensures that your meatloaf stays moist and delicious.
- Store the meatloaf in the refrigerator for up to 3-4 days. If you plan to eat it within this time frame, there's no need to freeze it.
- For longer storage, freeze the meatloaf. Place the wrapped meatloaf in a freezer-safe bag or container. Make sure to remove as much air as possible to prevent freezer burn.
- Label the container with the date. This helps you keep track of how long the meatloaf has been stored and ensures you use it within a safe time frame.
- When ready to eat, thaw the meatloaf in the refrigerator overnight. This slow thawing process helps maintain the texture and flavor of the meatloaf.
- Reheat the meatloaf in the oven at 350°F (175°C) until it reaches an internal temperature of 165°F (74°C). This ensures that it is heated through and safe to eat.
- Alternatively, you can reheat individual slices in the microwave. Place a slice on a microwave-safe plate, cover with a damp paper towel, and heat on medium power until warmed through.
- Serve the reheated Italian bison meatloaf with a fresh side of vegetables or a salad to complete your meal.
How to Reheat Leftovers
Oven Method: Preheat your oven to 350°F (175°C). Place the leftover Italian Bison Meatloaf in an oven-safe dish and cover it with aluminum foil to prevent it from drying out. Heat for about 20-25 minutes or until it reaches an internal temperature of 165°F (74°C). This method ensures the meatloaf remains moist and flavorful.
Microwave Method: Slice the meatloaf into individual portions for even heating. Place a slice on a microwave-safe plate and cover it with a microwave-safe lid or another plate to trap moisture. Heat on medium power for 2-3 minutes, checking halfway through to ensure it heats evenly. Add a splash of marinara sauce on top before microwaving to keep it juicy.
Stovetop Method: Heat a non-stick skillet over medium heat and add a small amount of olive oil. Place slices of the meatloaf in the skillet and cover with a lid. Cook for about 3-4 minutes on each side, or until heated through. This method adds a slight crispiness to the exterior while keeping the inside tender.
Steaming Method: Fill a pot with a small amount of water and bring it to a simmer. Place the meatloaf slices in a steamer basket and cover the pot with a lid. Steam for about 5-7 minutes or until heated through. This gentle method helps retain moisture and prevents the meatloaf from drying out.
Air Fryer Method: Preheat your air fryer to 350°F (175°C). Place slices of the meatloaf in the air fryer basket in a single layer. Heat for about 5-7 minutes, flipping halfway through. This method gives a nice crispy edge while keeping the inside moist.
Best Tools for This Recipe
Oven: Used to bake the meatloaf at a consistent temperature of 375°F (190°C).
Mixing bowl: A large bowl to combine and mix all the ingredients thoroughly.
Loaf pan: A pan to shape and bake the meatloaf in the oven.
Measuring cups: Used to measure out the breadcrumbs and marinara sauce accurately.
Measuring spoons: Used to measure out the dried oregano, dried basil, salt, and black pepper.
Grater: Used to grate the parmesan cheese.
Spatula: Useful for transferring the meatloaf mixture into the loaf pan and spreading the marinara sauce on top.
Meat thermometer: To check the internal temperature of the meatloaf, ensuring it reaches 160°F (71°C).
Knife: For slicing the meatloaf after it has rested.
Cutting board: A surface to slice the meatloaf on after it has rested.
How to Save Time on This Recipe
Prepare ingredients ahead: Measure and combine breadcrumbs, spices, and parmesan cheese in advance to streamline the process.
Use a food processor: Quickly mix the ground bison and other ingredients using a food processor for even distribution.
Preheat the oven early: Start preheating your oven before you begin mixing to save waiting time.
Line the loaf pan: Use parchment paper to line the loaf pan for easy removal and less cleanup.
Batch cook: Double the recipe and freeze one meatloaf for a quick meal later.

Italian Bison Meatloaf Recipe
Ingredients
Main Ingredients
- 1 lb Ground Bison
- 1 cup Breadcrumbs
- 1 Egg beaten
- ½ cup Grated Parmesan Cheese
- 1 teaspoon Dried Oregano
- 1 teaspoon Dried Basil
- 1 teaspoon Salt
- ½ teaspoon Black Pepper
- 1 cup Marinara Sauce divided
Instructions
- Preheat your oven to 375°F (190°C).
- In a large mixing bowl, combine the ground bison, breadcrumbs, beaten egg, grated Parmesan cheese, dried oregano, dried basil, salt, and black pepper.
- Add half of the marinara sauce to the mixture and mix well until all ingredients are evenly combined.
- Transfer the mixture to a loaf pan and shape it into a loaf.
- Spread the remaining marinara sauce over the top of the meatloaf.
- Bake in the preheated oven for about 60 minutes, or until the internal temperature reaches 160°F (71°C).
- Let the meatloaf rest for 10 minutes before slicing and serving.
Nutritional Value
Keywords
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