This Italian meatball sandwich casserole is a delightful twist on the classic meatball sub. It's a comforting dish that combines juicy meatballs, rich marinara sauce, and gooey mozzarella cheese, all layered on soft hoagie rolls. Perfect for a family dinner or a casual get-together, this casserole is sure to be a crowd-pleaser.
Most of the ingredients for this recipe are common pantry staples, but you might need to pick up a few items at the supermarket. Make sure you have ground beef, breadcrumbs, and hoagie rolls. If you don't usually stock marinara sauce or shredded mozzarella cheese, you'll need to grab those as well. The dried oregano and dried basil are essential for that authentic Italian flavor.

Ingredients for Italian Meatball Sandwich Casserole
Ground beef: The base for your meatballs, providing rich flavor and protein.
Breadcrumbs: Helps bind the meatballs together and adds texture.
Parmesan cheese: Adds a salty, nutty flavor to the meatballs.
Egg: Acts as a binder to hold the meatball mixture together.
Garlic powder: Provides a subtle garlic flavor without the need for fresh garlic.
Onion powder: Adds a mild onion flavor to the meatballs.
Dried oregano: A classic Italian herb that adds depth to the meatballs.
Dried basil: Another essential Italian herb that complements the oregano.
Marinara sauce: A tomato-based sauce that brings everything together with its rich flavor.
Hoagie rolls: The bread base for the casserole, soaking up all the delicious flavors.
Shredded mozzarella cheese: Melts beautifully over the casserole, adding a gooey, cheesy layer.
Technique Tip for This Recipe
When forming the meatballs, ensure they are uniform in size to promote even cooking. Using a small ice cream scoop or a tablespoon can help achieve this consistency. Additionally, lightly oil your hands to prevent the meat mixture from sticking while shaping the meatballs.
Suggested Side Dishes
Alternative Ingredients
ground beef - Substitute with ground turkey: Ground turkey is a leaner option and still provides a similar texture and flavor profile.
breadcrumbs - Substitute with crushed crackers: Crushed crackers can provide a similar binding effect and texture in the meatballs.
grated parmesan cheese - Substitute with grated pecorino romano: Pecorino romano has a similar salty and tangy flavor, making it a good alternative.
egg - Substitute with flax egg: A flax egg (1 tablespoon ground flaxseed mixed with 3 tablespoon water) can be used as a binder for a vegan option.
garlic powder - Substitute with fresh minced garlic: Fresh minced garlic provides a more robust and aromatic flavor.
onion powder - Substitute with finely chopped onions: Finely chopped onions can add a fresh and slightly sweet flavor.
dried oregano - Substitute with fresh oregano: Fresh oregano has a more vibrant and aromatic flavor.
dried basil - Substitute with fresh basil: Fresh basil offers a more intense and aromatic flavor.
marinara sauce - Substitute with tomato basil sauce: Tomato basil sauce can provide a similar base with a slightly different flavor profile.
hoagie rolls - Substitute with baguette slices: Baguette slices can provide a similar texture and are often more readily available.
shredded mozzarella cheese - Substitute with shredded provolone cheese: Provolone cheese melts well and has a slightly sharper flavor, making it a good alternative.
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How to Store or Freeze This Dish
Allow the Italian meatball sandwich casserole to cool completely before storing. This helps prevent condensation, which can make the dish soggy.
For short-term storage, transfer the casserole to an airtight container. Refrigerate for up to 3-4 days. When ready to enjoy, reheat in the oven at 350°F (175°C) until warmed through, approximately 15-20 minutes.
For longer storage, consider freezing. First, wrap the entire casserole dish tightly with plastic wrap, ensuring no air can enter. Follow this with a layer of aluminum foil for added protection.
If you prefer portioning, divide the casserole into individual servings. Place each serving in a freezer-safe container or wrap tightly with plastic wrap and then aluminum foil. Label with the date for easy tracking.
When ready to eat, thaw the casserole in the refrigerator overnight. Reheat in the oven at 350°F (175°C) until hot and bubbly, which should take about 25-30 minutes.
To maintain the texture of the hoagie rolls, you can reheat uncovered for the last 5-10 minutes to allow the top to crisp up.
Avoid microwaving the entire casserole as it can result in uneven heating and a less desirable texture. If using a microwave for individual portions, cover with a microwave-safe lid or wrap to retain moisture, and heat on medium power to ensure even warming.
For added freshness, consider adding a sprinkle of fresh basil or parmesan cheese after reheating. This can enhance the flavors and give the dish a freshly made feel.
How to Reheat Leftovers
Preheat your oven to 350°F (175°C). Place the leftover Italian Meatball Sandwich Casserole in an oven-safe dish. Cover it with aluminum foil to prevent the mozzarella cheese from drying out. Bake for 20-25 minutes or until heated through.
For a quicker option, use the microwave. Place a portion of the casserole on a microwave-safe plate. Cover it with a microwave-safe lid or another plate to retain moisture. Heat on medium power for 2-3 minutes, checking halfway through to ensure even heating.
If you prefer a crispy texture, use a toaster oven. Preheat the toaster oven to 350°F (175°C). Place the casserole on a toaster oven tray and cover it with foil. Heat for 15-20 minutes, then remove the foil for the last 5 minutes to let the cheese get bubbly and golden.
For stovetop reheating, place a non-stick skillet over medium heat. Add a small amount of olive oil or butter to the pan. Place a portion of the casserole in the skillet, cover with a lid, and heat for 5-7 minutes, stirring occasionally to ensure even heating.
If you have an air fryer, preheat it to 350°F (175°C). Place the casserole in the air fryer basket, making sure not to overcrowd it. Heat for 8-10 minutes, shaking the basket halfway through to ensure even heating and a crispy finish.
Essential Tools for This Recipe
Oven: Used to bake the meatballs and the casserole, ensuring everything is cooked through and the cheese is melted and bubbly.
Mixing bowl: Essential for combining the ground beef, breadcrumbs, parmesan, egg, and seasonings to form the meatball mixture.
Baking sheet: Used to place the formed meatballs on for baking in the oven.
Casserole dish: Used to layer the hoagie rolls, meatballs, marinara sauce, and mozzarella cheese for the final bake.
Measuring cups: Necessary for accurately measuring the breadcrumbs, parmesan cheese, and marinara sauce.
Measuring spoons: Used to measure out the garlic powder, onion powder, oregano, and basil.
Spatula: Helpful for mixing the meatball ingredients together thoroughly.
Knife: Used to slice the hoagie rolls if they are not pre-sliced.
Cutting board: Provides a safe surface for slicing the hoagie rolls.
Cheese grater: If not using pre-grated cheese, this tool is necessary for grating the parmesan and mozzarella cheese.
Serving spoon: Useful for layering the marinara sauce over the meatballs in the casserole dish.
How to Save Time Making This Dish
Prepare ingredients in advance: Mix ground beef, breadcrumbs, and spices the night before to save time.
Use pre-made marinara sauce: Opt for a quality jarred marinara sauce to cut down on prep time.
Pre-shredded cheese: Buy shredded mozzarella cheese to avoid the extra step of grating.
Bake meatballs in bulk: Double the meatball recipe and freeze half for future use.
Assemble in stages: Layer hoagie rolls, meatballs, and cheese in the casserole dish while the meatballs bake.
Italian Meatball Sandwich Casserole
Ingredients
Main Ingredients
- 1 lb ground beef
- ½ cup breadcrumbs
- ¼ cup grated Parmesan cheese
- 1 egg
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon dried oregano
- 1 teaspoon dried basil
- Salt and pepper to taste
- 1 jar marinara sauce
- 6 hoagie rolls
- 2 cups shredded mozzarella cheese
Instructions
- Preheat oven to 375°F (190°C).
- In a bowl, mix ground beef, breadcrumbs, Parmesan, egg, garlic powder, onion powder, oregano, basil, salt, and pepper.
- Form mixture into meatballs and place on a baking sheet.
- Bake meatballs for 20 minutes or until cooked through.
- In a casserole dish, layer hoagie rolls, meatballs, marinara sauce, and mozzarella cheese.
- Bake for 10 minutes or until cheese is melted and bubbly.
Nutritional Value
Keywords
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