This stuffed Italian meatloaf is a delightful twist on a classic comfort food. Packed with rich flavors and gooey mozzarella cheese, it promises to be a hit at any dinner table. The combination of ground beef, breadcrumbs, and parmesan cheese creates a savory base, while the Italian seasoning adds a burst of aromatic herbs.
While most of the ingredients for this recipe are common pantry staples, you might need to pick up Italian seasoning if you don't already have it. This blend of herbs typically includes basil, oregano, rosemary, and thyme, and it’s essential for achieving that authentic Italian flavor. Additionally, make sure you have shredded mozzarella cheese on hand for the stuffing.

Ingredients for Stuffed Italian Meatloaf Recipe
Ground beef: The main protein for the meatloaf, providing a rich and hearty flavor.
Breadcrumbs: Helps to bind the meatloaf together and adds a slight crunch.
Parmesan cheese: Adds a nutty and salty flavor to the meat mixture.
Eggs: Acts as a binder to hold the meatloaf together.
Salt: Enhances the overall flavor of the dish.
Black pepper: Adds a bit of heat and depth to the meatloaf.
Italian seasoning: A blend of herbs that gives the meatloaf its signature Italian flavor.
Shredded mozzarella cheese: The gooey, melty cheese that is stuffed inside the meatloaf.
Technique Tip for This Recipe
When flattening the meat mixture on the parchment paper, ensure it is of even thickness to promote uniform cooking. This will help the mozzarella cheese melt evenly and prevent any part of the meatloaf from being undercooked. Additionally, when rolling the meatloaf, use the parchment paper to guide and tighten the roll, which will help in keeping the stuffing intact and create a more compact loaf.
Suggested Side Dishes
Alternative Ingredients
ground beef - Substitute with ground turkey: Ground turkey is a leaner option and can provide a similar texture and flavor profile.
breadcrumbs - Substitute with crushed crackers: Crushed crackers can provide the same binding effect and add a slight crunch.
grated parmesan cheese - Substitute with grated pecorino romano: Pecorino romano has a similar salty and tangy flavor, making it a good alternative.
eggs - Substitute with flax eggs: Flax eggs (1 tablespoon ground flaxseed mixed with 3 tablespoon water per egg) can be used as a vegan binding agent.
salt - Substitute with soy sauce: Soy sauce can add a depth of umami flavor while providing the necessary saltiness.
black pepper - Substitute with white pepper: White pepper has a similar heat and can be used if you want a milder, less visually noticeable spice.
italian seasoning - Substitute with herbes de provence: Herbes de provence has a similar blend of herbs and can provide a slightly different but complementary flavor.
shredded mozzarella cheese - Substitute with shredded provolone cheese: Provolone has a similar meltability and flavor, making it a good alternative for stuffing.
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How To Store / Freeze This Dish
Allow the stuffed Italian meatloaf to cool completely at room temperature before storing or freezing. This helps prevent condensation, which can make the meatloaf soggy.
For storing in the refrigerator:
- Wrap the cooled meatloaf tightly in plastic wrap or aluminum foil to maintain its moisture and prevent it from absorbing any odors from other foods.
- Place the wrapped meatloaf in an airtight container or a resealable plastic bag.
- Store in the refrigerator for up to 3-4 days.
For freezing:
- Slice the meatloaf into individual portions for easier thawing and reheating.
- Wrap each slice tightly in plastic wrap, ensuring there are no air pockets.
- Place the wrapped slices in a single layer on a baking sheet and freeze for about 1-2 hours, or until solid. This prevents the slices from sticking together.
- Transfer the frozen slices to a resealable freezer bag or an airtight container. Label with the date for reference.
- Store in the freezer for up to 2-3 months.
Reheating:
- For refrigerated meatloaf: Preheat your oven to 350°F (175°C). Place the slices in a baking dish, cover with aluminum foil, and heat for about 20-25 minutes, or until warmed through.
- For frozen meatloaf: Thaw overnight in the refrigerator. Follow the same reheating instructions as for refrigerated meatloaf.
- Alternatively, you can reheat individual slices in the microwave. Place a slice on a microwave-safe plate, cover with a microwave-safe lid or another plate, and heat on medium power for 1-2 minutes, or until heated through.
How To Reheat Leftovers
Oven Method: Preheat your oven to 350°F (175°C). Place the leftover stuffed Italian meatloaf in an oven-safe dish. Cover it with aluminum foil to retain moisture. Heat for about 20-25 minutes, or until the internal temperature reaches 165°F (74°C). This method ensures the meatloaf remains juicy and flavorful.
Microwave Method: Slice the meatloaf into individual portions. Place a slice on a microwave-safe plate and cover it with a damp paper towel to prevent drying out. Microwave on medium power for 1-2 minutes, checking halfway through. This method is quick and convenient but may not retain the same texture as oven reheating.
Stovetop Method: Heat a non-stick skillet over medium heat. Add a small amount of olive oil or butter to the pan. Place slices of meatloaf in the skillet and cover with a lid. Heat for 3-4 minutes on each side, or until warmed through. This method gives a nice crust to the meatloaf while keeping it moist inside.
Air Fryer Method: Preheat your air fryer to 350°F (175°C). Place slices of meatloaf in the air fryer basket in a single layer. Heat for 5-7 minutes, or until the internal temperature reaches 165°F (74°C). This method provides a crispy exterior while keeping the interior tender.
Sous Vide Method: If you have a sous vide machine, set it to 165°F (74°C). Place the meatloaf slices in a vacuum-sealed bag or a resealable bag using the water displacement method. Submerge the bag in the water bath and heat for about 1 hour. This method ensures even reheating without drying out the meatloaf.
Best Tools for This Recipe
Oven: Used to preheat and bake the meatloaf at the specified temperature.
Large mixing bowl: Essential for combining the ground beef, breadcrumbs, grated parmesan, eggs, salt, pepper, and Italian seasoning.
Parchment paper: Helps in flattening the meat mixture into a rectangle and prevents sticking.
Baking dish: Used to place the rolled meatloaf for baking.
Measuring cups: Necessary for measuring ingredients like breadcrumbs and grated parmesan cheese.
Measuring spoons: Used to measure smaller quantities of ingredients like salt, pepper, and Italian seasoning.
Knife: Useful for slicing the meatloaf after it has rested.
Cutting board: Provides a surface for slicing the meatloaf.
Spatula: Helps in transferring the meatloaf to the baking dish.
Mixing spoon: Used to mix the ingredients in the large mixing bowl.
Rolling pin: Optional, but can help in flattening the meat mixture evenly.
How to Save Time on This Recipe
Prepare ingredients ahead: Measure and mix breadcrumbs, parmesan cheese, and seasonings in advance to streamline the process.
Use pre-shredded cheese: Save time by using pre-shredded mozzarella instead of shredding it yourself.
Flatten with a rolling pin: Use a rolling pin to quickly and evenly flatten the meat mixture on parchment paper.
Quick cleanup: Line your baking dish with parchment paper for easier cleanup after baking.

Stuffed Italian Meatloaf Recipe
Ingredients
Main Ingredients
- 1 lb Ground Beef
- 1 cup Breadcrumbs
- 1 cup Grated Parmesan Cheese
- 2 Eggs
- 1 teaspoon Salt
- 1 teaspoon Black Pepper
- 1 tablespoon Italian Seasoning
- 1 cup Shredded Mozzarella Cheese for stuffing
Instructions
- Preheat your oven to 375°F (190°C).
- In a large mixing bowl, combine ground beef, breadcrumbs, grated Parmesan, eggs, salt, pepper, and Italian seasoning. Mix well.
- On a piece of parchment paper, flatten the meat mixture into a rectangle.
- Sprinkle shredded mozzarella cheese evenly over the meat mixture, leaving a small border around the edges.
- Carefully roll the meat mixture into a loaf, sealing the edges to keep the cheese inside.
- Place the meatloaf in a baking dish and bake for 60 minutes, or until fully cooked.
- Let the meatloaf rest for 10 minutes before slicing and serving.
Nutritional Value
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